武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DNASE1 Rabbit pAb

Anti-DNASE1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217368

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217368
产品全名:   DNASE1 兔多抗
基因符号   DNL1; DRNI
UNIPROT ID:   P24855 (Gene Accession – BC029437 )
背景:   This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
抗原:   Fusion protein of human DNASE1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 217368(DNASE1 Antibody) at a dilution of 1/25(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the fusion protein and then with 217368(Anti-DNASE1 Antibody) at dilution 1/25.
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