武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DHCR7 Rabbit pAb

Anti-DHCR7 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217361

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217361
产品全名:   DHCR7 兔多抗
基因符号   SLOS
UNIPROT ID:   Q9UBM7 (Gene Accession – BC000054 )
背景:   This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by cognitive disability, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.
抗原:   Fusion protein of human DHCR7
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism, Cancer, Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217361(DHCR7 Antibody) at a dilution of 1/75(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217361(Anti-DHCR7 Antibody) at dilution 1/75.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 217361(Anti-DHCR7 Antibody) at a dilution of 1/75.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with fusion protein and then with D222232(Anti-DHCR7 Antibody) at dilution 1/75.
           引用文献