武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DCTN4 Rabbit pAb

Anti-DCTN4 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217349

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217349
产品全名:   DCTN4 兔多抗
基因符号   P62; DYN4
UNIPROT ID:   Q9UJW0 (Gene Accession – BC026323 )
背景:   Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.
抗原:   Fusion protein of human DCTN4
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 217349(DCTN4 Antibody) at a dilution of 1/30(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 217349(Anti-DCTN4 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 217349(Anti-DCTN4 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D222215(Anti-DCTN4 Antibody) at dilution 1/30.
           引用文献