| 货号: S221440 |
| 产品全名: IFNB1 兔多抗 |
| 基因符号 IFB; IFF; IFNB; IFN-beta |
| UNIPROT ID: P01574 (Gene Accession – NP_002167 ) |
| 背景: This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. |
| 抗原: Synthetic peptide of human IFNB1 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 30-150; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction, Cancer, Immunology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 221440(IFNB1 Antibody) at a dilution of 1/45(Cytoplasm or Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 221440(Anti-IFNB1 Antibody) at dilution 1/45. | 
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 221440(Anti-IFNB1 Antibody) at a dilution of 1/45. | 
In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D263031(Anti-IFNB1 Antibody) at dilution 1/45. |
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